Cosmetics and personal care products are in direct contact with our bodies and stay longer than many other products. For this reason, it is necessary for manufacturers and cosmetic formulators to determine whether their products may be toxic or pose a risk to consumers. Therefore, in order to protect consumers, it is necessary to conduct toxicity testing on cosmetics. Previously, standard test methods for determining toxicity were required to be conducted on animals. Now, the cosmetics and personal care industries are vigorously pushing to get rid of animal testing to ensure product safety. In Europe, the use of animals for cosmetic testing has long been banned (animal testing ban).